Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | LOX | P28300 | 1/20 | 0.44 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.44 |
| ▸ | LOXL4 | Q96JB6 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5928736 | 0.84 | MAPT (0.49) | MAPTKMT2AKDM4EMEN1THRB | |
| SCHEMBL5713339 | 0.83 | LOX (0.63) | MAPTKMT2AKDM4EMEN1THRB | |
| SCHEMBL6261308 | 0.79 | KMT2A (0.52) | MAPTKMT2AKDM4EGAAMEN1 | |
| SCHEMBL5928903 | 0.79 | MAPT (0.48) | MAPTKMT2AKDM4EMEN1THRB | |
| SCHEMBL5928796 | 0.75 | CES2 (0.42) | MAPTKMT2AKDM4EMEN1THRB | |
| SCHEMBL11861844 | 0.74 | MAPT (0.49) | MAPTKMT2AKDM4EGAAMEN1 | |
| SCHEMBL5928818 | 0.72 | MEN1 (0.50) | MAPTKMT2AKDM4EGAAMEN1 | |
| SCHEMBL22671454 | 0.72 | MAPT (0.37) | MAPTKMT2AKDM4EGAAMEN1 | |
| SCHEMBL22670032 | 0.71 | POLB (0.49) | MAPTKMT2AKDM4EMEN1THRB | |
| SCHEMBL5928770 | 0.70 | MAPT (0.67) | MAPTKMT2AKDM4EGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060229324-A1 | Quinazolin-4-one derivatives | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2006-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060229324-A1 | Quinazolin-4-one derivatives | HPGDS, PTGS1, PTGDR | MAPT 4875/4885KMT2A 2207/4885KDM4E 3855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.