Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 5/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 3/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.34 |
| ▸ | HTR3B | O95264 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.34 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.34 |
| ▸ | CYBB | P04839 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL953656 | 0.72 | F10 (0.45) | BACE1SLC2A1F10IRAK4KMT2A | |
| SCHEMBL27861068 | 0.67 | MEN1 (0.51) | KMT2A | |
| Trifluoroacetic Acid SCHEMBL20580644 | 0.61 | HTR7 (0.41) | BACE1HTR6HTR3A | |
| Trifluoroacetic Acid SCHEMBL6105775 | 0.61 | F10 (0.61) | F10 | |
| SCHEMBL19403739 | 0.60 | HTR3A (0.55) | HTR6HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL6195611 | 0.59 | HTR3A (0.61) | HTR6HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL11907097 | 0.59 | PIM1 (0.70) | IRAK4 | |
| Hydrochloric Acid SCHEMBL19385641 | 0.59 | ADRB2 (0.55) | HTR6HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL7833448 | 0.59 | CHEK1 (0.50) | BACE1KMT2ACHEK1 | |
| Trifluoroacetic Acid SCHEMBL27756881 | 0.58 | ADRB1 (0.47) | BACE1SLC2A1HTR6IRAK4HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1976586-A | Piperazine derivatives and their use for controlling pests | SYNGENTA PARTICIPATIONS AG (CH) | 2007-06-06 | — | — | CN | disclosed |