Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 6/20 | 0.41 |
| ▸ | HTR2B | P41595 | 6/20 | 0.41 |
| ▸ | HTR6 | P50406 | 6/20 | 0.41 |
| ▸ | HTR1A | P08908 | 5/20 | 0.41 |
| ▸ | HTR3A | P46098 | 4/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | HTR5A | P47898 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
| ▸ | HTR1D | P28221 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21894610 | 0.88 | HTR7 (0.50) | HTR7HTR2BHTR6HTR1AHTR3A | |
| SCHEMBL17739101 | 0.83 | HTR1A (0.54) | HTR7HTR2BHTR6HTR1AHTR3A | |
| SCHEMBL17738883 | 0.78 | MEN1 (0.41) | — | |
| SCHEMBL17739564 | 0.77 | NOTUM (0.47) | METAP2 | |
| SCHEMBL20916930 | 0.77 | POLB (0.47) | HTR7HTR2BHTR6HTR1AHTR3A | |
| SCHEMBL21894564 | 0.76 | CLK1 (0.47) | — | |
| SCHEMBL17738872 | 0.76 | TRPV1 (0.44) | HTR7HTR6HTR1AHTR2AHSP90AA1 | |
| SCHEMBL17738718 | 0.76 | ALDH1A1 (0.49) | HTR7HTR2BHTR6HTR1AHTR3A | |
| SCHEMBL17738580 | 0.75 | CYP11B1 (0.43) | — | |
| SCHEMBL23534492 | 0.75 | METAP2 (0.41) | METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11130738-B2 | Pharmaceutical compound | IOMET PHARMA LTD. (GB) | 2021-09-28 | — | — | US | disclosed |
| US-20200172492-A1 | PHARMACEUTICAL COMPOUND | IOMET PHARMA LTD. (GB) | 2020-06-04 | — | — | US | disclosed |
| US-10590086-B2 | Pharmaceutical compound | IOMET PHARMA LTD. (GB) | 2020-03-17 | — | — | US | disclosed |
| US-20180354908-A1 | PHARMACEUTICAL COMPOUND | IOMET PHARMA LTD. (GB) | 2018-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11130738-B2 | Pharmaceutical compound | IDO1, TDO2, IDO2 | HTR7 61/4885HTR2B 175/4885HTR6 21/4885 |
| US-20200172492-A1 | PHARMACEUTICAL COMPOUND | IDO1, TDO2, IDO2 | HTR7 61/4885HTR2B 175/4885HTR6 21/4885 |
| US-10590086-B2 | Pharmaceutical compound | IDO1, TDO2, IDO2 | HTR7 61/4885HTR2B 175/4885HTR6 21/4885 |
| US-20180354908-A1 | PHARMACEUTICAL COMPOUND | IDO1, TDO2, IDO2 | HTR7 61/4885HTR2B 175/4885HTR6 21/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.