Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 17/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | TDO2 | P48775 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27688635 | 0.73 | QPCT (0.33) | QPCT | |
| SCHEMBL2981910 | 0.62 | HDAC6 (0.34) | — | |
| SCHEMBL27708242 | 0.61 | CDK2 (0.36) | QPCT | |
| SCHEMBL9130426 | 0.59 | IDO1 (0.47) | IDO1TDO2TSHR | |
| SCHEMBL5147380 | 0.58 | ALDH1A1 (0.40) | TSHR | |
| SCHEMBL5149136 | 0.58 | MERTK (0.35) | — | |
| SCHEMBL2982192 | 0.56 | — | — | |
| SCHEMBL1568055 | 0.56 | SMN1; SMN2 (0.52) | QPCT | |
| SCHEMBL6989844 | 0.55 | TSHR (0.48) | QPCTIDO1TSHR | |
| SCHEMBL14416019 | 0.54 | QPCT (0.51) | QPCT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101115749-B | Aminopyrimidine compounds and methods of use | AMGEN INC | 2011-06-22 | — | — | CN | disclosed |
| CN-101115749-A | Aminopyrimidine compounds and methods of use | AMGEN INC (US) | 2008-01-30 | — | — | CN | disclosed |