Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PER2 | O15055 | 8/20 | 0.38 |
| ▸ | BDKRB2 | P30411 | 2/20 | 0.36 |
| ▸ | ACE | P12821 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27689173 | 0.83 | L3MBTL1 (0.38) | PER2TP53POLBTSHR | |
| SCHEMBL28766052 | 0.82 | TP53 (0.39) | PER2TP53 | |
| SCHEMBL5499122 | 0.82 | L3MBTL1 (0.37) | PER2TP53POLBTSHR | |
| SCHEMBL27670252 | 0.82 | PER2 (0.38) | PER2ACEL3MBTL3GAATSHR | |
| SCHEMBL27689238 | 0.81 | ALDH1A1 (0.45) | TP53POLBGAATSHRF10 | |
| SCHEMBL27689180 | 0.80 | FKBP1A (0.37) | PER2 | |
| SCHEMBL2859914 | 0.79 | SMN1; SMN2 (0.53) | — | |
| SCHEMBL2856411 | 0.71 | ACE (0.46) | PER2ACETP53POLB | |
| SCHEMBL15264280 | 0.69 | KDM5A (0.44) | POLBGAAF10 | |
| SCHEMBL2861902 | 0.69 | PER2 (0.40) | PER2ACEL3MBTL3POLBF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102093285-B | Cyclic amide derivatives, and their production and use as antithrombotic agents | TAKEDA PHARMACEUTICAL | 2013-10-16 | — | — | CN | disclosed |
| CN-1989104-B | Cyclic amide derivatives, their preparation and their use as antithrombotic agents | TAKEDA PHARMACEUTICAL | 2011-07-13 | — | — | CN | disclosed |
| CN-102093285-A | Cyclic amide derivatives, and their production and use as antithrombotic agents | TAKEDA PHARMACEUTICAL | 2011-06-15 | — | — | CN | disclosed |
| CN-1989104-A | Cyclic amide derivatives, their preparation and their use as antithrombotic agents | TAKEDA PHARMACEUTICAL (JP) | 2007-06-27 | — | — | CN | disclosed |