Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RAMP1 | O60894 | 3/20 | 0.39 |
| ▸ | CALCRL | Q16602 | 3/20 | 0.39 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.37 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.37 |
| ▸ | PER2 | O15055 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27689173 | 0.84 | L3MBTL1 (0.38) | TP53PER2KDM4E | |
| SCHEMBL5499122 | 0.83 | L3MBTL1 (0.37) | TP53PER2KDM4E | |
| SCHEMBL2853067 | 0.83 | SMN1; SMN2 (0.48) | TP53PLA2G10PLA2G5USP30GPR119 | |
| SCHEMBL27689294 | 0.82 | PER2 (0.38) | TP53PER2 | |
| SCHEMBL27689180 | 0.77 | FKBP1A (0.37) | CALCRLPER2 | |
| SCHEMBL27670252 | 0.76 | PER2 (0.38) | PER2KDM4E | |
| SCHEMBL27689238 | 0.75 | ALDH1A1 (0.45) | TP53KDM4EMAPTTHRB | |
| SCHEMBL8916277 | 0.74 | PLA2G10 (0.47) | PLA2G10PLA2G5PER2KDM4ESCN9A | |
| SCHEMBL6282329 | 0.73 | PLA2G10 (0.47) | PLA2G10PLA2G5KDM4EMAPTTHRB | |
| SCHEMBL27162983 | 0.71 | TP53 (0.50) | TP53PLA2G10PLA2G5SCN9ASCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102093285-B | Cyclic amide derivatives, and their production and use as antithrombotic agents | TAKEDA PHARMACEUTICAL | 2013-10-16 | — | — | CN | disclosed |
| CN-1989104-B | Cyclic amide derivatives, their preparation and their use as antithrombotic agents | TAKEDA PHARMACEUTICAL | 2011-07-13 | — | — | CN | disclosed |
| CN-102093285-A | Cyclic amide derivatives, and their production and use as antithrombotic agents | TAKEDA PHARMACEUTICAL | 2011-06-15 | — | — | CN | disclosed |
| CN-1989104-A | Cyclic amide derivatives, their preparation and their use as antithrombotic agents | TAKEDA PHARMACEUTICAL (JP) | 2007-06-27 | — | — | CN | disclosed |