Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 5/20 | 0.36 |
| ▸ | FAP | Q12884 | 4/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29588126 | 0.81 | HTT (0.37) | HTTALDH1A1HSD17B10SMN1; SMN2KDM4E | |
| SCHEMBL15392569 | 0.77 | HPGD (0.37) | HTTALDH1A1HSD17B10MAPT | |
| SCHEMBL31722100 | 0.74 | HCRTR2 (0.40) | EPHX2DPP4FAPDPP7 | |
| SCHEMBL29424739 | 0.74 | EPHX1 (0.50) | HSD17B10SMN1; SMN2THRBATML3MBTL1 | |
| SCHEMBL15414815 | 0.73 | RIPK1 (0.36) | ALDH1A1HSD17B10POLBDPP4 | |
| SCHEMBL2732689 | 0.73 | HPGD (0.38) | ALDH1A1HSD17B10SMN1; SMN2NPC1RAB9A | |
| SCHEMBL5312094 | 0.73 | KMT2A (0.36) | ALDH1A1HSD17B10SMN1; SMN2NPC1RAB9A | |
| SCHEMBL21293929 | 0.71 | DPP4 (0.40) | EPHX2DPP4FAP | |
| SCHEMBL4955982 | 0.71 | BBOX1 (0.35) | L3MBTL1POLBDPP4FAPDPP7 | |
| SCHEMBL27973416 | 0.71 | POLB (0.34) | ALDH1A1HSD17B10KDM4EL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101039941-A | Aminopiperidine derivatives, their preparation and use as melanocortin receptor agonists | SANOFI AVENTIS (FR) | 2007-09-19 | — | — | CN | disclosed |