Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 3/20 | 0.49 |
| ▸ | P4HB | P07237 | 13/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11563220 | 0.76 | PPME1 (0.57) | FBP1P4HBGRIN2DGRIN3BGRIN1 | |
| SCHEMBL1547532 | 0.75 | FBP1 (0.51) | FBP1P4HBGRIN2DGRIN3BGRIN1 | |
| SCHEMBL67236 | 0.75 | FBP1 (0.56) | FBP1P4HBGRIN2DGRIN3BGRIN1 | |
| SCHEMBL29463498 | 0.75 | FBP1 (0.56) | FBP1P4HBGRIN2DGRIN3BGRIN1 | |
| SCHEMBL27585129 | 0.75 | ENPP2 (0.48) | — | |
| SCHEMBL1687910 | 0.74 | FBP1 (0.65) | FBP1P4HBGRIN2DGRIN3BGRIN1 | |
| SCHEMBL2774364 | 0.74 | FBP1 (0.65) | FBP1P4HBGRIN2DGRIN3BGRIN1 | |
| SCHEMBL27605364 | 0.73 | TP53 (0.52) | FBP1MAOAMAOB | |
| SCHEMBL2657660 | 0.72 | FBP1 (0.53) | FBP1P4HBGRIN2DGRIN3BGRIN1 | |
| SCHEMBL29368312 | 0.72 | FBP1 (0.57) | FBP1P4HBGRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108698992-A | 2- cyano isoindoline derivatives for treating cancer | 特殊治疗有限公司 | 2018-10-23 | — | — | CN | claimed |
| CN-108698992-A | 2- cyano isoindoline derivatives for treating cancer | 特殊治疗有限公司 | 2018-10-23 | — | — | CN | disclosed |
| CN-101180266-B | As the alpha ketoamide compounds of cystatin | Vero Bay (US) | 2015-11-25 | — | — | CN | disclosed |
| CN-101180266-A | Alpha ketoamide compounds as cysteine protease inhibitors | APPLERA CORP (US) | 2008-05-14 | — | — | CN | disclosed |
| CN-101068783-A | Processes and intermediates for preparing cysteine protease inhibitors | BAYER SCHERING PHARMA AG (DE) | 2007-11-07 | — | — | CN | disclosed |