Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.31 |
| ▸ | TYR | P14679 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27689600 | 0.80 | ADRB2 (0.34) | ADRB2ADRB1ADRB3ADRA2AADRA2B | |
| SCHEMBL19249192 | 0.78 | GABRA1 (0.50) | ADRB2ADRB1ADRB3ADRA2AADRA2B | |
| SCHEMBL27691527 | 0.78 | ERN1 (0.32) | RNASEH1TYR | |
| SCHEMBL27691522 | 0.78 | MAPK1 (0.34) | RNASEH1TYR | |
| SCHEMBL27711676 | 0.77 | — | — | |
| SCHEMBL27691694 | 0.76 | ADRB2 (0.39) | ADRB2ADRB1ADRB3ADRA2AADRA2B | |
| SCHEMBL27798051 | 0.74 | CA3 (0.38) | RNASEH1TYR | |
| SCHEMBL27798056 | 0.74 | CA3 (0.42) | ADRA1ATYR | |
| SCHEMBL28177274 | 0.73 | ERN1 (0.45) | TYR | |
| SCHEMBL27641337 | 0.73 | HSP90AB1 (0.35) | ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101061105-A | Potentiators of glutamate receptors | LILLY CO ELI (US) | 2007-10-24 | — | — | CN | disclosed |