Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.42 |
| ▸ | VEGFA | P15692 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | DBH | P09172 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27693081 | 0.85 | HTR6 (0.50) | HDAC8HDAC6HTTLMNAMEN1 | |
| SCHEMBL27712752 | 0.82 | PLAU (0.50) | HDAC8HDAC6LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL27712747 | 0.78 | ALOX15 (0.39) | HTTLMNAKDM4EMEN1POLB | |
| SCHEMBL27650895 | 0.76 | ALDH1A1 (0.42) | HDAC8HDAC6HTTLMNAKDM4E | |
| SCHEMBL27970803 | 0.73 | ALDH1A1 (0.51) | HTTKDM4ESMN1; SMN2MEN1POLB | |
| SCHEMBL4392960 | 0.72 | MAPK14 (0.60) | HDAC8HDAC6HTTLMNAKDM4E | |
| SCHEMBL27838313 | 0.69 | HDAC8 (0.61) | HDAC8HDAC6HTTLMNAKDM4E | |
| SCHEMBL27529223 | 0.69 | ALDH1A1 (0.52) | HDAC8HDAC6KDM4ESMN1; SMN2NOTUM | |
| SCHEMBL4468724 | 0.69 | LMNA (0.58) | HDAC8HDAC6HTTLMNAKDM4E | |
| SCHEMBL28250545 | 0.69 | NOTUM (0.57) | HTTLMNAKDM4ETP53CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101010062-A | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER & GAMBLE (US) | 2007-08-01 | — | — | CN | disclosed |