Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MCOLN2 | Q8IZK6 | 4/20 | 0.46 |
| ▸ | MCOLN1 | Q9GZU1 | 4/20 | 0.46 |
| ▸ | MCOLN3 | Q8TDD5 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 5/20 | 0.44 |
| ▸ | MMP9 | P14780 | 4/20 | 0.44 |
| ▸ | MMP13 | P45452 | 3/20 | 0.44 |
| ▸ | MMP14 | P50281 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL48870 | 1.00 | ADAM17 (0.53) | ADAM17ALDH1A1MCOLN2MCOLN1MCOLN3 | |
| SCHEMBL27676230 | 1.00 | ADAM17 (0.53) | ADAM17ALDH1A1MCOLN2MCOLN1MCOLN3 | |
| SCHEMBL48288 | 1.00 | ADAM17 (0.53) | ADAM17ALDH1A1MCOLN2MCOLN1MCOLN3 | |
| SCHEMBL49324 | 0.89 | ALDH1A1 (0.49) | ALDH1A1MCOLN2MCOLN1MCOLN3GAA | |
| SCHEMBL49297 | 0.89 | ALDH1A1 (0.49) | ALDH1A1MCOLN2MCOLN1MCOLN3GAA | |
| SCHEMBL4385516 | 0.86 | MMP2 (0.59) | ADAM17ALDH1A1GAANPSR1MMP2 | |
| SCHEMBL48808 | 0.86 | MMP2 (0.59) | ADAM17ALDH1A1GAANPSR1MMP2 | |
| SCHEMBL48807 | 0.86 | MMP2 (0.59) | ADAM17ALDH1A1GAANPSR1MMP2 | |
| SCHEMBL54973 | 0.86 | MMP2 (0.59) | ADAM17ALDH1A1GAANPSR1MMP2 | |
| SCHEMBL4385195 | 0.85 | ADAM17 (0.42) | ADAM17ALDH1A1MCOLN2MCOLN1MCOLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101001834-B | Non-peptide inhibitors of matrix metalloproteinases | SOUTHERN RES INST | 2011-06-29 | — | — | CN | disclosed |
| CN-101001834-A | Non-peptide inhibitors of matrix metalloproteinases | SOUTHERN RES INST (US) | 2007-07-18 | — | — | CN | disclosed |