SCHEMBL27696754

SCHEMBL27696754

CCCCCCCC(C)C1=NCCO1

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ADH1B P00325 1/20 0.33
ADH1C P00326 1/20 0.33
ADH1A P07327 1/20 0.33
ADH4 P08319 1/20 0.33
ADH7 P40394 1/20 0.33
GPR84 Q9NQS5 1/20 0.33
ADRA2A P08913 1/20 0.33
ADRA2B P18089 1/20 0.33
ADRA2C P18825 1/20 0.33
OPRM1 P35372 1/20 0.32
SPHK1 Q9NYA1 1/20 0.32
LMNA P02545 1/20 0.31
PLA2G1B P04054 1/20 0.30
PLA2G2A P14555 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30670322 1.00 ADH1B (0.33) ADH1BADH1CADH1AADH4ADH7
SCHEMBL23466952 1.00 ADH1B (0.33) ADH1BADH1CADH1AADH4ADH7
SCHEMBL9787903 1.00 ADH1B (0.33) ADH1BADH1CADH1AADH4ADH7
SCHEMBL27678236 0.98 OPRM1 (0.33) ADH1BADH1CADH1AADH4ADH7
SCHEMBL23466953 0.93 ADRA2A (0.34) ADRA2AADRA2BADRA2C
SCHEMBL29117877 0.90 NOS3 (0.32) ADH1BADH1CADH1AADH4ADH7
SCHEMBL20755018 0.90 NOS3 (0.32) ADH1BADH1CADH1AADH4ADH7
SCHEMBL29117865 0.88 NOS3 (0.33) GPR84OPRM1
SCHEMBL27678227 0.85 ADRA2A (0.36) ADRA2AADRA2BADRA2C
SCHEMBL21034047 0.84 LMNA (0.31) ADH1BADH1CADH1AADH4ADH7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102234372-B Method for preparing block biodegradable polyesteramide UNIV BEIJING CHEMICAL 2012-08-29 CN disclosed
CN-102643422-A Preparation method for biodegradable aliphatic alternating polyester amide UNIV BEIJING CHEMICAL 2012-08-22 CN disclosed
CN-102079814-B Process for preparing aliphatic polyester amide containing short polyamide segment UNIV BEIJING CHEMICAL 2012-05-30 CN disclosed
CN-102234373-A Method for preparing biodegradable polyesteramide through chain extension UNIV BEIJING CHEMICAL 2011-11-09 CN disclosed
CN-102234372-A Method for preparing block biodegradable polyesteramide UNIV BEIJING CHEMICAL 2011-11-09 CN disclosed
CN-102079814-A Preparation method of aliphatic polyester amide containing short polyamide segment UNIV BEIJING CHEMICAL 2011-06-01 CN disclosed
CN-101585915-B Method for preparing biodegradable polyesteramide through chain extension UNIV BEIJING CHEMICAL 2011-04-20 CN disclosed
CN-101585915-A Method for preparing biodegradable polyesteramide through chain extension UNIV BEIJING CHEMICAL (CN) 2009-11-25 CN disclosed
CN-101020746-A Prepn process of biodegradable polyamidoester UNIV BEIJING CHEMICAL TECHNOLOGY (CN) 2007-08-22 CN disclosed