Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 6/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6751094 | 0.86 | NOTUM (0.57) | NOTUMKDM4ELMNAALDH1A1L3MBTL1 | |
| SCHEMBL9251071 | 0.84 | NOTUM (0.56) | NOTUMKDM4ELMNAALDH1A1L3MBTL1 | |
| SCHEMBL9740604 | 0.83 | KMT2A (0.44) | NOTUMKDM4ELMNAALDH1A1L3MBTL1 | |
| SCHEMBL27697369 | 0.81 | KDM4E (0.43) | TDP2NOTUMKDM4ELMNAALDH1A1 | |
| SCHEMBL680088 | 0.73 | ALDH1A1 (0.54) | NOTUMKDM4ELMNAALDH1A1L3MBTL1 | |
| SCHEMBL11462311 | 0.73 | NOTUM (0.59) | NOTUMKDM4ELMNAALDH1A1L3MBTL1 | |
| SCHEMBL9251057 | 0.73 | POLB (0.51) | NOTUMKDM4ELMNAALDH1A1L3MBTL1 | |
| SCHEMBL680519 | 0.73 | L3MBTL1 (0.63) | NOTUMKDM4ELMNAALDH1A1L3MBTL1 | |
| SCHEMBL11620900 | 0.72 | NOTUM (0.50) | NOTUMKDM4EALDH1A1 | |
| SCHEMBL11455750 | 0.72 | USP14 (0.43) | NOTUMKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-86100254-A | The method for preparing tertiary amine compounds | — | 1986-10-08 | — | — | CN | disclosed |