Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6751094 | 0.84 | NOTUM (0.57) | ALDH1A1KDM4ENPSR1NOTUMLMNA | |
| 4-Cyanophenol SCHEMBL27697371 | 0.83 | TDP2 (0.48) | ALDH1A1KDM4ENPSR1NOTUMLMNA | |
| SCHEMBL9251071 | 0.83 | NOTUM (0.56) | ALDH1A1KDM4ENPSR1NOTUMLMNA | |
| SCHEMBL680088 | 0.77 | ALDH1A1 (0.54) | KMT2AMEN1ALDH1A1KDM4ENOTUM | |
| SCHEMBL11462311 | 0.71 | NOTUM (0.59) | ALDH1A1KDM4ENPSR1NOTUMLMNA | |
| SCHEMBL9251057 | 0.71 | POLB (0.51) | KMT2AMEN1ALDH1A1KDM4ENPSR1 | |
| SCHEMBL680519 | 0.71 | L3MBTL1 (0.63) | KMT2AMEN1ALDH1A1KDM4ENOTUM | |
| SCHEMBL27697369 | 0.71 | KDM4E (0.43) | KMT2AALDH1A1KDM4ENPSR1NOTUM | |
| SCHEMBL1718000 | 0.67 | L3MBTL1 (0.51) | KMT2AMEN1KDM4ENPSR1NOTUM | |
| SCHEMBL31686290 | 0.66 | NOTUM (0.48) | KMT2AMEN1ALDH1A1KDM4ENOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5160364-A | Thiophene substituted acrylic derivatives; insecticides, plant growth regulators | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-11-03 | — | — | US | disclosed |