Naphthalene

Naphthalene

SCHEMBL27698306

O=S(=O)(O)Oc1cccc(O)c1O.c1ccc2ccccc2c1

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP1 P07148 1/20 0.49
ALOX15 P16050 3/20 0.44
HSD17B10 Q99714 3/20 0.44
ALDH1A1 P00352 3/20 0.44
KDM4E B2RXH2 2/20 0.44
ALOX12 P18054 2/20 0.44
LMNA P02545 2/20 0.44
HPGD P15428 2/20 0.44
MAPT P10636 2/20 0.44
TP53 P04637 2/20 0.44
CYP3A4 P08684 1/20 0.44
MAPK1 P28482 1/20 0.44
KMT2A Q03164 5/20 0.42
GAA P10253 4/20 0.42
MEN1 O00255 4/20 0.42
ESR1 P03372 3/20 0.42
ESR2 Q92731 3/20 0.42
SLC22A6 Q4U2R8 1/20 0.41
CA1 P00915 3/20 0.39
CA2 P00918 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1879537 0.92 LMNA (0.50) FABP1ALOX15HSD17B10ALDH1A1KDM4E
SCHEMBL29382842 0.82 HSD11B1 (0.50) FABP1ALOX15HSD17B10ALDH1A1KDM4E
SCHEMBL235067 0.82 HSD11B1 (0.50) FABP1ALOX15HSD17B10ALDH1A1KDM4E
SCHEMBL9541027 0.80 HSD11B1 (0.49) FABP1ALOX15HSD17B10ALDH1A1KDM4E
Ammonia Solution, Strong SCHEMBL11405643 0.80 HSD11B1 (0.49) FABP1ALOX15HSD17B10ALDH1A1KDM4E
SCHEMBL3698749 0.78 ALDH1A1 (0.44) FABP1ALOX15HSD17B10ALDH1A1KDM4E
SCHEMBL514247 0.77 SLC22A6 (0.53) FABP1ALDH1A1LMNAMAPTSLC22A6
SCHEMBL275479 0.77 SLC22A6 (0.51) FABP1HSD17B10ALDH1A1KDM4EHPGD
SCHEMBL1890372 0.77 FABP1 (0.41) FABP1ALOX15HSD17B10ALDH1A1KDM4E
SCHEMBL8770826 0.76 SLC22A6 (0.47) FABP1HSD17B10MAPTSLC22A6CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110511939-A Nucleosides, nucleotide and nucleic acid of modification and application thereof MODERNATX INC 2019-11-29 CN disclosed
CN-103974724-B Modified nucleosides, nucleotides and nucleic acids and uses thereof 现代泰克斯公司 2019-08-30 CN disclosed
CN-103974724-A Modified nucleosides, nucleotides and nucleic acids and uses thereof modeRNA Therapeutics 2014-08-06 CN disclosed
CN-101023187-A KSV-2 type specific immunoassays using glycoprotein G2 peptides BIO RAD LABORATORIES (US) 2007-08-22 CN disclosed