Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CDK2 | P24941 | 2/20 | 0.39 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1879537 | 0.84 | LMNA (0.50) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| Naphthalene SCHEMBL27698306 | 0.78 | FABP1 (0.49) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| SCHEMBL3480009 | 0.75 | ALDH1A1 (0.54) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| SCHEMBL2900971 | 0.73 | ALDH1A1 (0.42) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| SCHEMBL28833567 | 0.72 | ALDH1A1 (0.50) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| SCHEMBL78824 | 0.71 | TDP1 (0.41) | ALDH1A1LMNAKDM4ETP53MAPK1 | |
| SCHEMBL28100659 | 0.71 | HSD11B1 (0.51) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| 3-Methoxycatechol SCHEMBL29636518 | 0.71 | TP53 (0.79) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| 3-Methoxycatechol SCHEMBL18396654 | 0.71 | TP53 (0.79) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| Catechol SCHEMBL1143840 | 0.71 | CA2 (0.53) | ALDH1A1LMNAHPGDALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120119420-A1 | Nano metric composite ceramic component | HOWMEDICA OSTEONICS CORP. | 2012-05-17 | — | — | US | claimed |