Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | RXRA | P19793 | 5/20 | 0.42 |
| ▸ | RXRB | P28702 | 5/20 | 0.42 |
| ▸ | RXRG | P48443 | 4/20 | 0.42 |
| ▸ | ASPH | Q12797 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15276310 | 0.87 | KIF11 (0.47) | CES2KIF11CA12CA1CA2 | |
| SCHEMBL23370105 | 0.86 | CES2 (0.43) | CES2KIF11KDM4EALDH1A1RXRA | |
| SCHEMBL20178562 | 0.84 | ALDH1A1 (0.46) | CES2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL29338525 | 0.84 | ALDH1A1 (0.46) | CES2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL3661976 | 0.84 | CES2 (0.44) | CES2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL2769865 | 0.82 | CA12 (0.48) | CES2KIF11CA12CA1CA2 | |
| SCHEMBL27847003 | 0.81 | CES2 (0.42) | CES2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL25489233 | 0.81 | CES2 (0.42) | CES2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL28740117 | 0.80 | XDH (0.43) | CES2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL13598475 | 0.80 | AKR1C2 (0.46) | CES2KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104177349-A | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC | 2014-12-03 | — | — | CN | disclosed |
| US-20140080877-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, LLC (US) | 2014-03-20 | — | — | US | disclosed |
| US-20140080877-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, LLC (US) | 2014-03-20 | — | — | US | disclosed |
| US-20140080877-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, LLC (US) | 2014-03-20 | — | — | US | disclosed |
| US-8623896-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION, LLC (US) | 2014-01-07 | — | — | US | disclosed |
| US-8623896-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION, LLC (US) | 2014-01-07 | — | — | US | disclosed |
| US-8623896-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION, LLC (US) | 2014-01-07 | — | — | US | disclosed |
| EP-2592079-A2 | Insecticidal compounds | Syngenta Participations AG. (CH) | 2013-05-15 | — | — | EP | disclosed |
| EP-2592079-A2 | Insecticidal compounds | Syngenta Participations AG. (CH) | 2013-05-15 | — | — | EP | disclosed |
| EP-2518068-A2 | Insecticidal compounds | Syngenta Participations AG. (CH) | 2012-10-31 | — | — | EP | disclosed |
| EP-2518068-A2 | Insecticidal compounds | Syngenta Participations AG. (CH) | 2012-10-31 | — | — | EP | disclosed |
| EP-2238132-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2012-08-01 | — | — | EP | disclosed |
| EP-2238132-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2012-08-01 | — | — | EP | disclosed |
| CN-101910161-A | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG | 2010-12-08 | — | — | CN | disclosed |
| US-20100279999-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-11-04 | — | — | US | disclosed |
| US-20100279999-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-11-04 | — | — | US | disclosed |
| US-20100279999-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-11-04 | — | — | US | disclosed |
| EP-2238132-A2 | INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2010-10-13 | — | — | EP | disclosed |
| WO-2009080250-A2 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2009-07-02 | — | — | WO | disclosed |
| WO-2009080250-A2 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2009-07-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100279999-A1 | INSECTICIDAL COMPOUNDS | CHRM1, ACHE, CHRM2 | CES2 1912/4885KIF11 2390/4885CA12 2615/4885 |
| US-20140080877-A1 | INSECTICIDAL COMPOUNDS | CHRM1, ACHE, CHRM2 | CES2 1909/4885KIF11 2375/4885CA12 2667/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.