Glutamic Acid

Glutamic Acid

SCHEMBL939699

C#C.C#C.N[C@@H](CCC(=O)O)C(=O)O

nearest known ligand 0.90

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GRM8 O00222 2/20 0.90
▸ GRM6 O15303 2/20 0.90
▸ GRM7 Q14831 2/20 0.90
▸ GRM4 Q14833 2/20 0.90
▸ GSR P00390 2/20 0.90
▸ GRIN2D O15399 1/20 0.90
▸ GRIN3B O60391 1/20 0.90
▸ CYP1A2 P05177 1/20 0.90
▸ GRIK1 P39086 1/20 0.90
▸ GRM5 P41594 1/20 0.90
▸ GRIA1 P42261 1/20 0.90
▸ GRIA2 P42262 1/20 0.90
▸ GRIA3 P42263 1/20 0.90
▸ SLC1A3 P43003 1/20 0.90
▸ SLC1A2 P43004 1/20 0.90
▸ SLC1A1 P43005 1/20 0.90
▸ GRIA4 P48058 1/20 0.90
▸ GRIN1 Q05586 1/20 0.90
▸ GRIN2A Q12879 1/20 0.90
▸ GRIK2 Q13002 1/20 0.90

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
D-Glutamate SCHEMBL939698 1.00 GRM8 (0.90) GRM8GRM6GRM7GRM4GSR
Glutamic Acid SCHEMBL1554237 0.95 GRM8 (1.00) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL1330566 0.95 GRM8 (1.00) GRM8GRM6GRM7GRM4GSR
Glutamic Acid SCHEMBL5704264 0.95 GRM8 (1.00) GRM8GRM6GRM7GRM4GSR
Glutamic Acid SCHEMBL2202 0.95 GRM8 (1.00) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL410241 0.95 GRM8 (1.00) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL1332144 0.95 GRM8 (1.00) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL1330917 0.95 GRM8 (1.00) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL1332007 0.95 GRM8 (1.00) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL43222 0.95 GRM8 (1.00) GRM8GRM6GRM7GRM4GSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130040020-A1 Methods and Compositions for Preparing Consumables with Optical Shifting Properties SEGAN INDUSTRIES, INC. 2013-02-14 — — US disclosed
US-20110008498-A1 Methods and Compositions for Preparing Consumables with Optical Shifting Properties SEGAN INDUSTRIES, INC. 2011-01-13 — — US disclosed
US-7776371-B2 Methods and compositions for preparing consumables with optical shifting properties SEGAN INDUSTRIES INC. (US) 2010-08-17 — — US disclosed
EP-2128610-A2 Ingestibles possessing intrinsic color change Segan Industries, Inc. (US) 2009-12-02 — — EP disclosed
US-20070071680-A1 Methods and compositions for preparing consumables with optical shifting properties SEGAN INDUSTRIES, INC. 2007-03-29 — — US disclosed
US-6866863-B2 Ingestibles possessing intrinsic color change SEGAN INDUSTRIES, INC. (US) 2005-03-15 — — US disclosed
US-6607744-B1 Polydiacetylene homopolymer triggered to change color at transition temperature; foods, drinks SEGAN INDUSTRIES 2003-08-19 — — US disclosed
US-20030143188-A1 Ingestibles possessing intrinsic color change SEGAN INDUSTRIES 2003-07-31 — — US disclosed
US-20030103905-A1 Methods and compositions for preparing consumables with optical shifting properties SEGAN INDUSTRIES 2003-06-05 — — US disclosed
EP-1297333-A2 INGESTIBLES POSSESSING INTRINSIC COLOR CHANGE Segan Industries, Inc. (US) 2003-04-02 — — EP disclosed
US-20020034475-A1 Ingestibles possessing intrinsic color change SEGAN INDUSTRIES 2002-03-21 — — US disclosed
WO-2002000920-A2 INGESTIBLES POSSESSING INTRINSIC COLOR CHANGE SEGAN INDUSTRIES, INC. (US) 2002-01-03 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030103905-A1 Methods and compositions for preparing consumables with optical shifting properties TAS2R46, THEM6, TAS2R41 GRM8 3344/4885GRM6 855/4885GRM7 3511/4885
US-20020034475-A1 Ingestibles possessing intrinsic color change TAS2R46, THEM6, TAS2R16 GRM8 3561/4885GRM6 1225/4885GRM7 3553/4885
US-20070071680-A1 Methods and compositions for preparing consumables with optical shifting properties TAS2R46, THEM6, TAS2R41 GRM8 3344/4885GRM6 855/4885GRM7 3511/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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