Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 11/20 | 0.70 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.55 |
| ▸ | BRAF | P15056 | 2/20 | 0.53 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.51 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27720628 | 0.90 | CSF1R (0.63) | CSF1RCYP11B2KCNMA1SGMS2MEN1 | |
| SCHEMBL3934183 | 0.82 | CSF1R (1.00) | CSF1RBRAF | |
| SCHEMBL3933275 | 0.80 | CSF1R (0.72) | CSF1RCYP11B2BRAFKCNMA1MEN1 | |
| SCHEMBL1276793 | 0.80 | CSF1R (1.00) | CSF1RBRAFMEN1KMT2A | |
| SCHEMBL3934893 | 0.79 | CSF1R (0.85) | CSF1RCYP11B2BRAF | |
| M-Xylene SCHEMBL27720422 | 0.78 | BRAF (0.58) | CSF1RCYP11B2BRAFLMNA | |
| SCHEMBL3934404 | 0.78 | CSF1R (0.83) | CSF1RCYP11B2BRAF | |
| SCHEMBL21021112 | 0.77 | RAB9A (0.54) | CSF1RMEN1LMNAHTTKMT2A | |
| Bromobenzene SCHEMBL27720387 | 0.76 | CYP11B2 (0.57) | CSF1RCYP11B2MEN1LMNAKMT2A | |
| SCHEMBL5814463 | 0.75 | CSF1R (0.70) | CSF1RCYP11B2KCNMA1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101128454-A | Pyridine carboxamide derivatives for use as anticancer agents | ASTRAZENECA AB (SE) | 2008-02-20 | — | — | CN | disclosed |