Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 11/20 | 0.63 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.57 |
| ▸ | NAMPT | P43490 | 1/20 | 0.53 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.53 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.52 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27699868 | 0.90 | CSF1R (0.70) | CSF1RCYP11B2KCNMA1SGMS2MEN1 | |
| SCHEMBL21021112 | 0.83 | RAB9A (0.54) | CSF1RMEN1RAB9AKMT2A | |
| SCHEMBL3933275 | 0.81 | CSF1R (0.72) | CSF1RCYP11B2KCNMA1CYP11B1MEN1 | |
| SCHEMBL3934404 | 0.79 | CSF1R (0.83) | CSF1RCYP11B2CYP11B1RAB9A | |
| SCHEMBL3934893 | 0.79 | CSF1R (0.85) | CSF1RCYP11B2NAMPT | |
| M-Xylene SCHEMBL27720422 | 0.78 | BRAF (0.58) | CSF1RCYP11B2NAMPTCYP11B1 | |
| Bromobenzene SCHEMBL27720387 | 0.78 | CYP11B2 (0.57) | CSF1RCYP11B2NAMPTCYP11B1MEN1 | |
| SCHEMBL3934183 | 0.78 | CSF1R (1.00) | CSF1RRAB9A | |
| SCHEMBL30926678 | 0.77 | ALDH1A1 (0.64) | CSF1RCYP11B2NAMPTMEN1KMT2A | |
| SCHEMBL27181116 | 0.77 | ALDH1A1 (0.64) | CSF1RCYP11B2NAMPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101128454-A | Pyridine carboxamide derivatives for use as anticancer agents | ASTRAZENECA AB (SE) | 2008-02-20 | — | — | CN | disclosed |