Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11557429 | 0.87 | MMP12 (0.38) | PDE3BPDE3AKDM4EALDH1A1 | |
| SCHEMBL11560192 | 0.86 | LMNA (0.38) | SMN1; SMN2 | |
| SCHEMBL11558220 | 0.86 | KCNE1 (0.34) | — | |
| SCHEMBL11558080 | 0.86 | MAPT (0.36) | AKT1PDE3BPDE3AKDM4EALDH1A1 | |
| SCHEMBL11559728 | 0.84 | GAA (0.37) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL11559426 | 0.83 | TRPV1 (0.35) | — | |
| SCHEMBL11560034 | 0.83 | SMN1; SMN2 (0.37) | CA9KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL11565708 | 0.83 | PTGS2 (0.34) | CA9 | |
| SCHEMBL11560946 | 0.83 | ALPL (0.34) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL11556858 | 0.80 | BRD4 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4134974-A | Imidazo[5,1-c][1,4]benzoxazin-1-one | CARLO ERBA S. P. A. (IT) | 1979-01-16 | — | — | US | disclosed |