Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | NMT2 | O60551 | 1/20 | 0.31 |
| ▸ | NMT1 | P30419 | 1/20 | 0.31 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Zinc Ion SCHEMBL2582011 | 0.82 | FAAH (0.35) | FAAH | |
| SCHEMBL2580853 | 0.80 | FAAH (0.43) | FAAHSLC6A5 | |
| SCHEMBL2580857 | 0.80 | FAAH (0.43) | FAAHSLC6A5 | |
| Zinc Ion SCHEMBL2577653 | 0.78 | FAAH (0.31) | FAAHNMT2NMT1 | |
| SCHEMBL2583384 | 0.74 | FAAH (0.41) | FAAHNMT2NMT1 | |
| SCHEMBL2583386 | 0.74 | FAAH (0.41) | FAAHNMT2NMT1 | |
| SCHEMBL19951022 | 0.74 | NFKB1 (0.39) | FAAH | |
| SCHEMBL2582839 | 0.74 | KMT2A (0.53) | FAAH | |
| SCHEMBL2576072 | 0.72 | KMT2A (0.51) | FAAH | |
| Zinc Ion SCHEMBL2582837 | 0.72 | FAAH (0.40) | FAAHSLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100367949-C | Melanin extinguisher | OGA RES INC (JP) | 2008-02-13 | — | — | CN | claimed |