Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL143892 | 0.80 | ALDH1A1 (0.38) | ALDH1A1KMT2ATDP1MEN1CES2 | |
| SCHEMBL181841 | 0.77 | ALDH1A1 (0.74) | ALDH1A1KMT2ATDP1MEN1POLB | |
| SCHEMBL6609769 | 0.73 | RAB9A (0.58) | KMT2AMEN1POLBPTPN1RAB9A | |
| SCHEMBL27705691 | 0.73 | FAAH (0.44) | CES1 | |
| SCHEMBL218652 | 0.72 | ALDH1A1 (0.54) | ALDH1A1KMT2ATDP1MEN1POLB | |
| SCHEMBL3953437 | 0.72 | ALDH1A1 (0.73) | ALDH1A1KMT2ATDP1MEN1POLB | |
| SCHEMBL5215655 | 0.72 | KMT2A (0.66) | ALDH1A1KMT2ATDP1MEN1POLB | |
| SCHEMBL11124310 | 0.71 | KMT2A (0.50) | ALDH1A1KMT2ATDP1MEN1POLB | |
| SCHEMBL1727779 | 0.71 | — | — | |
| Water SCHEMBL29275067 | 0.71 | ALDH1A1 (0.52) | ALDH1A1KMT2ATDP1MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101184726-A | 2-arylpropionic acid derivatives and pharmaceutical compositions containing them | DOMPE PHA R MA SPA RES & MFG (IT) | 2008-05-21 | — | — | CN | disclosed |