Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | UBE2M | P61081 | 1/20 | 0.34 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1595904 | 0.87 | MAPT (0.42) | MAPTRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL27688542 | 0.83 | F11 (0.35) | MAPTRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL28770423 | 0.81 | GRIK1 (0.42) | MAPTGRIK1POLB | |
| SCHEMBL2569122 | 0.75 | MAPT (0.40) | MAPTRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL2568640 | 0.74 | MAPT (0.39) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL2572024 | 0.73 | P2RX7 (0.48) | MAPTRAB9ASMN1; SMN2LMNAGRIK1 | |
| SCHEMBL2565935 | 0.72 | ALOX5 (0.41) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL13197808 | 0.72 | SLC6A3 (0.37) | MAPTRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL1594449 | 0.71 | MEN1 (0.41) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL2572465 | 0.71 | MAPK1 (0.39) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101128455-A | Heterocyclylamide-substituted imidazoles | BAYER HEALTHCARE AG (DE) | 2008-02-20 | — | — | CN | disclosed |