SCHEMBL27709166

SCHEMBL27709166

O=C(O)Cc1snnc1C1CC1

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ABCC8 Q09428 1/20 0.35
KCNJ11 Q14654 1/20 0.35
EPHX2 P34913 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2860777 0.72 ABCC8 (0.42) ABCC8KCNJ11EPHX2
SCHEMBL10841293 0.69 KDM4E (0.32)
SCHEMBL27797900 0.67 KDM4E (0.30)
SCHEMBL27797611 0.67 PTGDR2 (0.30)
SCHEMBL27820176 0.63 GABRR1 (0.31)
SCHEMBL27799032 0.63 GABRR1 (0.31)
SCHEMBL8763542 0.58 CYP1A2 (0.38)
SCHEMBL9278180 0.54 SLC6A12 (0.57)
SCHEMBL27749017 0.54 PTGDR2 (0.37)
SCHEMBL8434293 0.52 MAPT (0.49)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101128445-B 4-cyclopropyl-1,2,3-thiadiazole derivative, agrohorticultural plant disease controlling agent, and method for using the same NIHON NOHYAKU CO LTD 2012-01-18 CN claimed
CN-101128445-A 4-cyclopropyl-1,2,3-thiadiazole derivative, agrohorticultural plant disease controlling agent, and method for using the same NIHON NOHYAKU CO LTD (JP) 2008-02-20 CN claimed
CN-101128445-B 4-cyclopropyl-1,2,3-thiadiazole derivative, agrohorticultural plant disease controlling agent, and method for using the same NIHON NOHYAKU CO LTD 2012-01-18 CN disclosed
CN-101128445-A 4-cyclopropyl-1,2,3-thiadiazole derivative, agrohorticultural plant disease controlling agent, and method for using the same NIHON NOHYAKU CO LTD (JP) 2008-02-20 CN disclosed