Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1736253 | 0.79 | MTNR1A (0.55) | KMT2AMEN1MAPTTSHRPOLB | |
| SCHEMBL6677730 | 0.79 | ENPP2 (0.41) | KMT2AMEN1MAPTTSHRTP53 | |
| SCHEMBL31108381 | 0.78 | POLB (0.53) | KMT2AMEN1POLBALDH1A1PKM | |
| SCHEMBL27762863 | 0.78 | POLB (0.53) | KMT2AMEN1POLBALDH1A1PKM | |
| SCHEMBL18905642 | 0.77 | APP (0.51) | APPKMT2AMEN1MAPTMAPK1 | |
| SCHEMBL29281753 | 0.77 | ALDH1A1 (0.44) | KMT2AMEN1MAPTMAPK1TSHR | |
| SCHEMBL27899109 | 0.77 | RAB9A (0.46) | KMT2AMEN1MAPTMAPK1TSHR | |
| SCHEMBL30543838 | 0.75 | KMT2A (0.63) | KMT2AMEN1MAPTMAPK1TSHR | |
| SCHEMBL361514 | 0.75 | KMT2A (0.63) | KMT2AMEN1MAPTMAPK1TSHR | |
| SCHEMBL27487535 | 0.75 | APP (0.39) | APPKMT2AMEN1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101394829-A | Composition for the oxidative dyeing of keratin fibers and method for using such a composition | PROCTER & GAMBLE (US) | 2009-03-25 | — | — | CN | claimed |
| CN-101394829-A | Composition for the oxidative dyeing of keratin fibers and method for using such a composition | PROCTER & GAMBLE (US) | 2009-03-25 | — | — | CN | disclosed |
| CN-101022810-A | Novel biaromatic compounds which activate peroxisome proliferator activated receptor-like receptors and their use in cosmetic or pharmaceutical compositions | GALDERMA RES & DEV (FR) | 2007-08-22 | — | — | CN | disclosed |