Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.52 |
| ▸ | PPARA | Q07869 | 4/20 | 0.52 |
| ▸ | PPARD | Q03181 | 2/20 | 0.52 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.47 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.46 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.46 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.46 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.46 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.46 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.46 |
| ▸ | HTR6 | P50406 | 4/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | FABP3 | P05413 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4119321 | 0.76 | ACLY (0.51) | PPARGPPARAPPARDAGTR1PSEN1 | |
| SCHEMBL3527594 | 0.75 | PPARG (0.66) | PPARGPPARAPPARDPSEN1PSEN2 | |
| SCHEMBL12093313 | 0.71 | HTR6 (0.70) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL1443267 | 0.71 | CA2 (0.43) | AGTR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL1466410 | 0.70 | PPARG (0.75) | PPARGPPARAPPARD | |
| SCHEMBL7378048 | 0.70 | AGTR1 (0.55) | AGTR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3033927 | 0.70 | HTR6 (0.71) | PPARGPPARAPPARDHTR6HTR1A | |
| SCHEMBL15565794 | 0.70 | AGTR1 (0.48) | AGTR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3040501 | 0.69 | IDE (0.55) | PPARGPPARAPPARDHTR6PTGDR2 | |
| SCHEMBL3523667 | 0.69 | PPARG (0.76) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101248044-B | Indole compounds | FOURNIER LAB SA | 2012-05-30 | — | — | CN | disclosed |
| CN-101248044-A | Novel indole compounds | FOURNIER LAB SA (FR) | 2008-08-20 | — | — | CN | disclosed |