Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 6/20 | 0.47 |
| ▸ | THRA | P10827 | 5/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27726801 | 0.86 | PTPN11 (0.55) | THRBTHRAPTPN11TSHRTP53 | |
| SCHEMBL27706193 | 0.85 | MEN1 (0.54) | THRBTHRAPTPN11FLT3TSHR | |
| SCHEMBL5096583 | 0.81 | MAOA (0.52) | THRBTHRAPTPN11TSHRALDH1A1 | |
| SCHEMBL27733999 | 0.80 | CA12 (0.61) | THRBTHRATSHRALDH1A1LMNA | |
| SCHEMBL8185682 | 0.79 | HSD17B10 (0.57) | THRBTHRAPTPN11TSHRALDH1A1 | |
| SCHEMBL27713618 | 0.79 | KDM4E (0.51) | THRBTHRAALDH1A1NPC1RAB9A | |
| SCHEMBL34470190 | 0.79 | ALDH1A1 (0.46) | FLT3TSHRALDH1A1TP53NPC1 | |
| SCHEMBL14974765 | 0.78 | TSHR (0.51) | TSHRALDH1A1LMNATP53HSD17B10 | |
| SCHEMBL10430684 | 0.78 | THRA (0.54) | THRBTHRAPTPN11TSHRTP53 | |
| SCHEMBL14974769 | 0.78 | TSHR (0.51) | TSHRALDH1A1LMNATP53HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101186577-A | Liquid crystal monomer with reaction character and preparation method thereof | NORTHWEST IND UNIVERSITY (CN) | 2008-05-28 | — | — | CN | disclosed |