Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL6514880 | 0.92 | TSHR (0.48) | TSHRLMNAALOX12ACHEALDH1A1 | |
| Toluene SCHEMBL512992 | 0.92 | TSHR (0.48) | TSHRLMNAALOX12ACHEALDH1A1 | |
| Toluene SCHEMBL27551962 | 0.92 | TSHR (0.48) | TSHRLMNAALOX12ACHEALDH1A1 | |
| Toluene SCHEMBL27659900 | 0.90 | LMNA (0.46) | TSHRLMNAALOX12ACHEALDH1A1 | |
| Toluene SCHEMBL1148280 | 0.87 | LMNA (0.58) | TSHRLMNAALOX12ACHEALDH1A1 | |
| Toluene SCHEMBL28202360 | 0.85 | LMNA (0.55) | TSHRLMNAALOX12ACHEALDH1A1 | |
| Toluene SCHEMBL28236662 | 0.85 | LMNA (0.55) | TSHRLMNAALOX12ACHEALDH1A1 | |
| Toluene SCHEMBL27751750 | 0.85 | LMNA (0.55) | TSHRLMNAALOX12ACHEALDH1A1 | |
| Toluene SCHEMBL29249545 | 0.85 | SMN1; SMN2 (0.59) | TSHRLMNAALOX12ACHEALDH1A1 | |
| Toluene SCHEMBL22071089 | 0.83 | ALDH1A1 (0.55) | TSHRLMNAALDH1A1TDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101123995-B | Stilbene derivatives and their use for binding and imaging amyloid plaques | UNIV PENNSYLVANIA | 2011-11-16 | — | — | CN | disclosed |
| CN-101123995-A | Stilbene derivatives and their use for binding and imaging amyloid plaques | UNIV PENNSYLVANIA (US) | 2008-02-13 | — | — | CN | disclosed |