Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | COMT | P21964 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13658228 | 0.79 | LMNA (0.43) | MEN1KMT2APTGDR2ELANELMNA | |
| SCHEMBL1639585 | 0.74 | ALOX15 (0.43) | PTGDR2 | |
| SCHEMBL1639813 | 0.74 | CYP1A2 (0.47) | MEN1KMT2AELANELMNAHTT | |
| SCHEMBL27714808 | 0.71 | ELANE (0.40) | MEN1KMT2AELANEKDM4E | |
| SCHEMBL2363211 | 0.69 | CCR1 (0.44) | MEN1KMT2AELANEHTTKDM4E | |
| SCHEMBL9996736 | 0.67 | FAAH (0.45) | MEN1KMT2ALMNAKDM4E | |
| SCHEMBL27735636 | 0.67 | L3MBTL1 (0.46) | MEN1KMT2APTGDR2ELANELMNA | |
| SCHEMBL27714803 | 0.65 | MAOB (0.39) | MEN1KMT2AELANEKDM4E | |
| SCHEMBL27735688 | 0.65 | ELANE (0.41) | MEN1KMT2AELANELMNAKDM4E | |
| SCHEMBL2489396 | 0.63 | ELANE (0.43) | MEN1KMT2AELANEHTTCOMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155203-B1 | AZAINDAZOLE COMPOUNDS AND METHODS OF USE | CHEMOCENTRYX INC (US) | 2018-10-17 | — | — | EP | disclosed |