SCHEMBL2772007

SCHEMBL2772007

CC(C#N)CSC(=S)c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 1/20 0.34
HDAC4 P56524 1/20 0.34
HDAC1 Q13547 1/20 0.34
HDAC7 Q8WUI4 1/20 0.34
HDAC2 Q92769 1/20 0.34
HDAC10 Q969S8 1/20 0.34
HDAC11 Q96DB2 1/20 0.34
HDAC8 Q9BY41 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34
HDAC9 Q9UKV0 1/20 0.34
HDAC5 Q9UQL6 1/20 0.34
RAB9A P51151 2/20 0.33
NPC1 O15118 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ALDH1A1 P00352 3/20 0.32
MAPT P10636 2/20 0.32
TSHR P16473 1/20 0.32
CTSL P07711 3/20 0.32
CTSB P07858 1/20 0.32
CTSS P25774 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28362420 0.84 MEN1 (0.38) ALDH1A1MAPTIDO1
SCHEMBL29155252 0.81 HDAC3 (0.31) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL27692603 0.80 HDAC3 (0.39) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL22634315 0.77
SCHEMBL4661226 0.76 TSHR (0.33) ALDH1A1MAPTTSHRCTSLCTSB
SCHEMBL5494921 0.76 HDAC3 (0.39) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL28459699 0.76 TAAR1 (0.42) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL12892651 0.75 ALDH1A1 (0.36) RAB9ASMN1; SMN2ALDH1A1MAPTTSHR
SCHEMBL22092183 0.74 CTSL (0.36) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL2373732 0.74 ALDH1A1 (0.38) HDAC3HDAC4HDAC1HDAC7HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116209579-A Pigment dispersant composition, method for producing same, pigment dispersion, and active energy ray-curable inkjet ink 大日精化工业株式会社 2023-06-02 CN disclosed
US-11371015-B2 Graft polymer, temperature-responsive substrate for cell culture using the same and production method therefor, as well as liquid chromatographic carrier having the novel graft polymer immomibilized thereon and liquid chromatographic method using the same Sakai, Hideaki (JP) 2022-06-28 US disclosed
US-20210180011-A1 NOVEL GRAFT POLYMER, TEMPERATURE-RESPONSIVE SUBSTRATE FOR CELL CULTURE USING THE SAME AND PRODUCTION METHOD THEREFOR, AS WELL AS LIQUID CHROMATOGRAPHIC CARRIER HAVING THE NOVEL GRAFT POLYMER IMMOMIBILIZED THEREON AND LIQUID CHROMATOGRAPHIC METHOD USING THE SAME DKS CO. LTD. (JP) 2021-06-17 US disclosed
EP-2963071-B1 TEMPERATURE-RESPONSIVE SUBSTRATE FOR CELL CULTURE AND METHOD FOR PRODUCING SAID SUBSTRATE SAKAI HIDEAKI (JP) 2021-03-24 EP disclosed
EP-2958987-B1 METHOD OF STORING OR PRESERVING LIVE HUMAN STEM CELLS IN STASIS UNIV SHEFFIELD (GB) 2020-10-07 EP disclosed
CN-105899656-B Culture medium for stem cells 谢菲尔德大学 2020-07-24 CN disclosed
US-20200216802-A1 NOVEL GRAFT POLYMER, TEMPERATURE-RESPONSIVE SUBSTRATE FOR CELL CULTURE USING THE SAME AND PRODUCTION METHOD THEREFOR, AS WELL AS LIQUID CHROMATOGRAPHIC CARRIER HAVING THE NOVEL GRAFT POLYMER IMMOMIBILIZED THEREON AND LIQUID CHROMATOGRAPHIC METHOD USING THE SAME SAKAI, HIDEAKI (JP) 2020-07-09 US disclosed
US-20190169567-A1 NOVEL GRAFT POLYMER, TEMPERATURE-RESPONSIVE SUBSTRATE FOR CELL CULTURE USING THE SAME AND PRODUCTION METHOD THEREFOR, AS WELL AS LIQUID CHROMATOGRAPHIC CARRIER HAVING THE NOVEL GRAFT POLYMER IMMOBILIZED THEREON AND LIQUID CHROMATOGRAPHIC METHOD USING THE SAME SAKAI, HIDEAKI (JP) 2019-06-06 US disclosed
US-10150946-B2 Media for stem cells THE UNIVERSITY OF SHEFFIELD (GB) 2018-12-11 US disclosed
US-20160115441-A1 NOVEL GRAFT POLYMER, TEMPERATURE-RESPONSIVE SUBSTRATE FOR CELL CULTURE USING THE SAME AND PRODUCTION METHOD THEREFOR, AS WELL AS LIQUID CHROMATOGRAPHIC CARRIER HAVING THE NOVEL GRAFT POLYMER IMMOBILIZED THEREON AND LIQUID CHROMATOGRAPHIC METHOD USING THE SAME SAKAI, HIDEAKI (JP) 2016-04-28 US disclosed
US-7662986-B2 Polymerization with living characteristics COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2010-02-16 US disclosed
US-20090036608-A1 CHLOROPRENE-BASED BLOCK COPOLYMER, SOAPLESS POLYCHLOROPRENE-BASED LATEX, AND PROCESSES FOR PRODUCING THE SAME TOSOH CORPORATION (JP) 2009-02-05 US disclosed
US-20080139836-A1 Polymerization with living characteristics LE TAM PHUONG 2008-06-12 US disclosed
US-20080139764-A1 Polymerization with living characteristics COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2008-06-12 US disclosed
US-7250479-B2 Polymerization with living characteristics E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-07-31 US disclosed
US-20070148594-A1 Polymers, resist compositions and patterning process SHIN-ETSU CHEMICAL CO., LTD. 2007-06-28 US disclosed
US-20040171777-A1 Polymerization with living characteristics COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2004-09-02 US disclosed
EP-0910587-B1 POLYMERIZATION WITH LIVING CHARACTERISTICS DU PONT (US) 2001-12-12 EP disclosed
EP-0910587-A1 POLYMERIZATION WITH LIVING CHARACTERISTICS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-04-28 EP disclosed
WO-1998001478-A1 POLYMERIZATION WITH LIVING CHARACTERISTICS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-01-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080139836-A1 Polymerization with living characteristics UQCRB, MTR, UQCRC2 HDAC3 2448/4885HDAC4 2260/4885HDAC1 2626/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.