Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3715907 | 0.89 | ALDH1A1 (0.37) | ALDH1A1CYP1A2CYP3A4CYP2C19TSHR | |
| SCHEMBL3263484 | 0.81 | SMN1; SMN2 (0.38) | ALDH1A1CYP1A2CYP3A4CYP2C19CYP19A1 | |
| SCHEMBL31212629 | 0.79 | IDO1 (0.37) | ALDH1A1CYP1A2CYP3A4CYP2C19GAA | |
| SCHEMBL21916099 | 0.78 | KMT2A (0.42) | ALDH1A1CYP3A4TSHRKMT2APOLB | |
| SCHEMBL15669258 | 0.75 | HDAC3 (0.35) | ALDH1A1CYP3A4TSHRGAAKMT2A | |
| SCHEMBL7584115 | 0.75 | MAPT (0.47) | ALDH1A1GAAKMT2APOLBHDAC3 | |
| SCHEMBL163065 | 0.75 | NOS1 (0.52) | ALDH1A1CYP1A2CYP3A4CYP2C19HDAC3 | |
| SCHEMBL23112205 | 0.74 | PHGDH (0.52) | ALDH1A1CYP1A2CYP3A4CYP2C19TSHR | |
| SCHEMBL2772007 | 0.74 | HDAC3 (0.34) | ALDH1A1TSHRPOLBHDAC3HDAC4 | |
| SCHEMBL28556797 | 0.74 | SMN1; SMN2 (0.38) | ALDH1A1CYP19A1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2478021-B1 | Nitrile rubbers and production of same in organic solvents | LANXESS DEUTSCHLAND GMBH (DE) | 2015-11-04 | — | — | EP | claimed |
| US-9023914-B2 | Nitrile rubbers and production thereof in organic solvents | LANXESS DEUTSCHLAND GMBH (DE) | 2015-05-05 | — | — | US | claimed |
| US-20140235744-A1 | PROCESS FOR PRODUCING NITRILE RUBBERS IN ORGANIC SOLVENTS | LANXESS DEUTSCHLAND GMBH (DE) | 2014-08-21 | — | — | US | claimed |
| US-20120283351-A1 | NITRILE RUBBERS AND PRODUCTION THEREOF IN ORGANIC SOLVENTS | LANXESS DEUTSCHLAND GMBH (DE) | 2012-11-08 | — | — | US | claimed |
| US-10858455-B2 | Process for the production of water and solvent-free nitrile rubbers | ARLANXEO DEUTSCHLAND GMBH (DE) | 2020-12-08 | — | — | US | disclosed |
| US-20160369014-A1 | PROCESS FOR THE PRODUCTION OF WATER AND SOLVENT-FREE NITRILE RUBBERS | ARLANXEO DEUTSCHLAND GMBH (DE) | 2016-12-22 | — | — | US | disclosed |
| US-9469697-B2 | Process for the production of water and solvent-free nitrile rubbers | LANXESS DEUTSCHLAND GMBH (DE) | 2016-10-18 | — | — | US | disclosed |
| CN-102498140-B | Nitrile rubbers and production thereof in organic solvents | LANXESS DEUTSCHLAND GMBH | 2015-06-24 | — | — | CN | disclosed |
| US-9023914-B2 | Nitrile rubbers and production thereof in organic solvents | LANXESS DEUTSCHLAND GMBH (DE) | 2015-05-05 | — | — | US | disclosed |
| US-20140357801-A1 | Nitrile rubbers coupled via bisdihydropyrazole groups, production thereof and use thereof | LANXESS DEUTSCHLAND GMBH (DE) | 2014-12-04 | — | — | US | disclosed |
| US-20140235744-A1 | PROCESS FOR PRODUCING NITRILE RUBBERS IN ORGANIC SOLVENTS | LANXESS DEUTSCHLAND GMBH (DE) | 2014-08-21 | — | — | US | disclosed |
| US-20130211031-A1 | PROCESS FOR THE PRODUCTION OF WATER AND SOLVENT-FREE NITRILE RUBBERS | LANXESS International S.A. (CH) | 2013-08-15 | — | — | US | disclosed |
| EP-2550301-A1 | PROCESS FOR THE PRODUCTION OF WATER AND SOLVENT-FREE NITRILE RUBBERS | Lanxess Deutschland GmbH (DE) | 2013-01-30 | — | — | EP | disclosed |
| US-20120283351-A1 | NITRILE RUBBERS AND PRODUCTION THEREOF IN ORGANIC SOLVENTS | LANXESS DEUTSCHLAND GMBH (DE) | 2012-11-08 | — | — | US | disclosed |
| EP-2368916-B1 | Process for the production of water and solvent-free nitrile rubbers | LANXESS INT SA (CH) | 2012-08-22 | — | — | EP | disclosed |
| CN-102498140-A | Nitrile rubbers and production thereof in organic solvents | LANXESS DEUTSCHLAND GMBH | 2012-06-13 | — | — | CN | disclosed |
| WO-2011117194-A1 | PROCESS FOR THE PRODUCTION OF WATER AND SOLVENT-FREE NITRILE RUBBERS | LANXESS DEUTSCHLAND GMBH (DE) | 2011-09-29 | — | — | WO | disclosed |
| EP-2368916-A1 | Process for the production of water and solvent-free nitrile rubbers | LANXESS International SA (CH) | 2011-09-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140357801-A1 | Nitrile rubbers coupled via bisdihydropyrazole groups, production thereof and use thereof | CYP2E1, NOS3, NOS2 | ALDH1A1 992/4885CYP1A2 50/4885CYP3A4 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.