Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPB1 | P04792 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MYOC | Q99972 | 1/20 | 0.44 |
| ▸ | ERN1 | O75460 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16814441 | 0.82 | HSPB1 (0.68) | HSPB1ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL349039 | 0.82 | ERN1 (0.62) | ALDH1A1KMT2AMEN1MAPTERN1 | |
| SCHEMBL2527480 | 0.82 | ALDH1A1 (0.50) | HSPB1ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL14451771 | 0.79 | TLR9 (0.61) | HSPB1ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL31556425 | 0.79 | LMNA (0.50) | ALDH1A1KMT2AERN1SRD5A2CYP2C9 | |
| SCHEMBL2536648 | 0.79 | LMNA (0.50) | ALDH1A1KMT2AERN1SRD5A2CYP2C9 | |
| Ethylene SCHEMBL7400535 | 0.79 | ERN1 (0.59) | ALDH1A1KMT2AMEN1MAPTERN1 | |
| SCHEMBL5175967 | 0.79 | SOS1 (0.44) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL13111360 | 0.79 | ALDH1A1 (0.50) | HSPB1ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL1982719 | 0.78 | HSPB1 (0.62) | HSPB1ALDH1A1KDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101298427-B | Diaryl urea compound and use thereof | GUANGZHOU INST BIOMED & HEALTH | 2012-03-21 | — | — | CN | disclosed |
| CN-101298427-A | Diaryl urea compound and use thereof | GUANGZHOU INST BIOMED & HEALTH (CN) | 2008-11-05 | — | — | CN | disclosed |