Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.45 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.41 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.41 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.41 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27627079 | 0.86 | HCAR2 (0.52) | ANO1KMT2AALDH1A1MEN1HPGD | |
| SCHEMBL28776560 | 0.84 | TYR (0.53) | TAAR1ANO1MGLL | |
| SCHEMBL30898243 | 0.84 | MGLL (0.43) | SMN1; SMN2NPC1RAB9AMGLL | |
| SCHEMBL27718558 | 0.83 | TAAR1 (0.45) | TAAR1ALDH1A1NPC1RAB9AMGLL | |
| SCHEMBL27832828 | 0.83 | LOXL2 (0.46) | ALDH1A1SMN1; SMN2NPC1RAB9AMGLL | |
| SCHEMBL27787225 | 0.83 | MAOA (0.42) | ALDH1A1SMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL23630606 | 0.82 | NPC1 (0.55) | ALDH1A1SMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL27718552 | 0.80 | CNR1 (0.43) | SMN1; SMN2RAB9ACNR1MGLL | |
| SCHEMBL13667239 | 0.79 | MAOB (0.49) | TAAR1KMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL27809141 | 0.79 | CYP2D6 (0.47) | KMT2AMEN1SMN1; SMN2RAB9ATRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101300239-A | 7- (2-amino-1-hydroxy-ethyl) -4-hydroxybenzothiazol-2 (3H) -one derivatives as beta 2 adrenoreceptor agonists | ASTRAZENECA AB (SE) | 2008-11-05 | — | — | CN | disclosed |