Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27801313 | 0.87 | RAB9A (0.57) | RAB9AADRB2ADRB1ADRB3MAOB | |
| SCHEMBL28096698 | 0.81 | ADRB2 (0.46) | RECQLRAB9AADRB2TSHRMEN1 | |
| SCHEMBL4688326 | 0.81 | MAOB (0.53) | CYP2D6CYP2C9CYP2C19RECQLRAB9A | |
| SCHEMBL30898243 | 0.80 | MGLL (0.43) | RECQLRAB9AMAPTSMN1; SMN2 | |
| SCHEMBL28776560 | 0.80 | TYR (0.53) | — | |
| SCHEMBL27579050 | 0.80 | CYP2D6 (0.49) | CYP2D6CYP2C9CYP2C19RECQLRAB9A | |
| SCHEMBL27720152 | 0.79 | TAAR1 (0.45) | RAB9ATRPV1MAOBMEN1KMT2A | |
| SCHEMBL27832828 | 0.79 | LOXL2 (0.46) | CYP2D6CYP2C9CYP2C19RAB9ATSHR | |
| SCHEMBL27718558 | 0.79 | TAAR1 (0.45) | CYP2D6CYP2C19RAB9AHTTLMNA | |
| SCHEMBL27787225 | 0.79 | MAOA (0.42) | RAB9AADRB2ADRB1ADRB3MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101784551-A | bicycloaniline derivative | BANYU PHARMA CO LTD | 2010-07-21 | — | — | CN | disclosed |