Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.42 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | VNN1 | O95497 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.39 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.39 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28772042 | 0.84 | PPARD (0.46) | CNR1RAB9ASMN1; SMN2 | |
| SCHEMBL28776560 | 0.81 | TYR (0.53) | MGLL | |
| SCHEMBL30898243 | 0.81 | MGLL (0.43) | GLARAB9AMGLLSMN1; SMN2PDK1 | |
| SCHEMBL27832828 | 0.80 | LOXL2 (0.46) | GLARAB9AMGLLSMN1; SMN2 | |
| SCHEMBL27718558 | 0.80 | TAAR1 (0.45) | GLALMNARAB9AMGLL | |
| SCHEMBL27787225 | 0.80 | MAOA (0.42) | GLARAB9AMGLLSMN1; SMN2 | |
| SCHEMBL27720152 | 0.80 | TAAR1 (0.45) | CNR1RAB9AMGLLSMN1; SMN2 | |
| SCHEMBL23630606 | 0.79 | NPC1 (0.55) | GLARAB9AMGLLSMN1; SMN2 | |
| SCHEMBL30898286 | 0.76 | NPC1 (0.46) | LMNARAB9ASMN1; SMN2PDK1PDK2 | |
| SCHEMBL27809141 | 0.76 | CYP2D6 (0.47) | LMNATBXA2RRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101137628-A | Non-anilinic derivatives of isothiazol-3(2h)-one 1,1-dioxides as liver x receptor modulators | ASTRAZENECA AB (SE) | 2008-03-05 | — | — | CN | disclosed |