Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.58 |
| ▸ | NPC1 | O15118 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.57 |
| ▸ | HTT | P42858 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 9/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | RAF1 | P04049 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.50 |
| ▸ | RELA | Q04206 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27740984 | 0.91 | S1PR1 (0.51) | RAB9ANPC1ALDH1A1HPGDLMNA | |
| SCHEMBL27720139 | 0.90 | ALDH1A1 (0.52) | RAB9ANPC1ALDH1A1HPGDLMNA | |
| SCHEMBL27720157 | 0.84 | MAPT (0.64) | RAB9ANPC1LMNAHTTMAPT | |
| SCHEMBL27740982 | 0.84 | KDR (0.53) | RAB9ANPC1SMN1; SMN2RAF1EPHX2 | |
| SCHEMBL27741147 | 0.83 | EPHX2 (0.56) | RAF1EPHX2 | |
| SCHEMBL27740985 | 0.83 | EPHX2 (0.62) | EPHX2 | |
| SCHEMBL27720100 | 0.81 | BRAF (0.63) | RAB9ANPC1ALDH1A1HTTMAPT | |
| SCHEMBL27740975 | 0.79 | RAB9A (0.50) | RAB9ANPC1HPGDMAPTTSHR | |
| SCHEMBL27720191 | 0.78 | CDK8 (0.55) | RAB9ANPC1ALDH1A1LMNAHTT | |
| SCHEMBL27720155 | 0.78 | BRAF (0.64) | RAB9ANPC1HTTMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101298427-B | Diaryl urea compound and use thereof | GUANGZHOU INST BIOMED & HEALTH | 2012-03-21 | — | — | CN | disclosed |
| CN-101298427-A | Diaryl urea compound and use thereof | GUANGZHOU INST BIOMED & HEALTH (CN) | 2008-11-05 | — | — | CN | disclosed |