Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.53 |
| ▸ | CCR2 | P41597 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30728403 | 0.78 | CYP19A1 (0.57) | AGTR1KDM4EALDH1A1L3MBTL1MEN1 | |
| SCHEMBL4821857 | 0.73 | MCL1 (0.46) | AGTR1POLBFOLH1THRBL3MBTL1 | |
| SCHEMBL14809705 | 0.72 | CCR2 (0.70) | CCR2POLBKDM4EALDH1A1HPGD | |
| SCHEMBL6723373 | 0.71 | ALDH1A1 (0.59) | KDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL5070885 | 0.70 | LMNA (0.55) | KDM4EALDH1A1L3MBTL1MEN1LMNA | |
| SCHEMBL3277702 | 0.69 | CCR2 (0.56) | CCR2POLBKDM4EALDH1A1HPGD | |
| SCHEMBL6302591 | 0.69 | CCR2 (1.00) | CCR2POLBKDM4EALDH1A1HPGD | |
| SCHEMBL9236147 | 0.69 | CCR2 (0.59) | CCR2POLBKDM4EALDH1A1HPGD | |
| SCHEMBL612585 | 0.68 | POLB (0.62) | CCR2POLBKDM4EALDH1A1HPGD | |
| SCHEMBL3187789 | 0.67 | LMNA (0.58) | KDM4EALDH1A1THRBL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100434420-C | Compounds that block dipeptidyl peptidase IV | SANWA KAGAKU KENKYUSHO CO (JP) | 2008-11-19 | — | — | CN | disclosed |