Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27742974 | 0.89 | LMNA (0.38) | ALDH1A1LMNAL3MBTL1MAPK14ALOX5 | |
| SCHEMBL28776251 | 0.83 | SLC16A3 (0.39) | ALDH1A1LMNAL3MBTL1MAPK14ALOX5 | |
| SCHEMBL7500570 | 0.81 | LMNA (0.46) | ALDH1A1LMNAL3MBTL1MAPK14HPGD | |
| SCHEMBL3179284 | 0.76 | CDK8 (0.52) | MAPK14HPGDCCNCCDK8JAK2 | |
| SCHEMBL27944346 | 0.74 | ALDH1A1 (0.51) | ALDH1A1LMNAL3MBTL1ALOX5HPGD | |
| SCHEMBL27794319 | 0.74 | MAP3K7 (0.39) | ALDH1A1LMNAMAPK14HPGDKDM4E | |
| SCHEMBL27767837 | 0.73 | ALDH1A1 (0.58) | ALDH1A1LMNAL3MBTL1ALOX5CNR1 | |
| SCHEMBL27767901 | 0.73 | LMNA (0.46) | ALDH1A1LMNAL3MBTL1MAPK14ALOX5 | |
| SCHEMBL15995545 | 0.70 | ALDH1A1 (0.56) | ALDH1A1LMNAL3MBTL1MAPK14ALOX5 | |
| SCHEMBL15007941 | 0.69 | MAPK14 (0.56) | MAPK14HPGDCCNCCDK8JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101316841-A | Arylmethylene urea derivative and use thereof | TORAY INDUSTRIES (JP) | 2008-12-03 | — | — | CN | disclosed |