Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.35 |
| ▸ | BCL2 | P10415 | 2/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
| ▸ | NPY2R | P49146 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27722384 | 0.89 | ALDH1A1 (0.39) | LMNAALDH1A1MAPK14SMN1; SMN2L3MBTL1 | |
| SCHEMBL28776251 | 0.81 | SLC16A3 (0.39) | LMNAALDH1A1MAPK14SMN1; SMN2L3MBTL1 | |
| SCHEMBL7500570 | 0.80 | LMNA (0.46) | LMNAALDH1A1MAPK14SMN1; SMN2L3MBTL1 | |
| SCHEMBL3185137 | 0.75 | MAPK14 (0.58) | MAPK14HPGDGAA | |
| SCHEMBL27944346 | 0.72 | ALDH1A1 (0.51) | LMNAALDH1A1L3MBTL1HPGDMDM2 | |
| SCHEMBL27767837 | 0.72 | ALDH1A1 (0.58) | LMNAALDH1A1L3MBTL1HTTALOX5 | |
| SCHEMBL27767901 | 0.71 | LMNA (0.46) | LMNAALDH1A1MAPK14L3MBTL1ALOX5 | |
| SCHEMBL27794319 | 0.70 | MAP3K7 (0.39) | LMNAALDH1A1MAPK14SMN1; SMN2HPGD | |
| SCHEMBL27903551 | 0.69 | ABL1 (0.44) | LMNAALDH1A1MAPK14SMN1; SMN2HTT | |
| SCHEMBL27742977 | 0.68 | LMNA (0.49) | LMNAALDH1A1SMN1; SMN2L3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101316841-A | Arylmethylene urea derivative and use thereof | TORAY INDUSTRIES (JP) | 2008-12-03 | — | — | CN | disclosed |