SCHEMBL27722650

SCHEMBL27722650

CC(C)(C)O[SiH2]C=Cc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.39
MAOB P27338 1/20 0.39
CYP2C19 P33261 1/20 0.38
ALOX15 P16050 1/20 0.37
EGFR P00533 1/20 0.37
KDM4E B2RXH2 1/20 0.37
MEN1 O00255 1/20 0.37
USP2 O75604 1/20 0.37
ALDH1A1 P00352 1/20 0.37
TP53 P04637 1/20 0.37
CYP3A4 P08684 1/20 0.37
MAPT P10636 1/20 0.37
HPGD P15428 1/20 0.37
KMT2A Q03164 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
TRPV1 Q8NER1 1/20 0.37
HSD17B10 Q99714 1/20 0.37
CHAT P28329 2/20 0.36
RELA Q04206 2/20 0.36
NFE2L2 Q16236 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12802373 0.83 TRPA1 (0.40) TRPA1MAOBCYP2C19ALOX15EGFR
SCHEMBL28064263 0.82 RELA (0.40) TRPA1MAOBCYP2C19KDM4EALDH1A1
SCHEMBL28438264 0.82 RELA (0.40) TRPA1MAOBCYP2C19ALOX15EGFR
SCHEMBL1468386 0.77 TRPA1 (0.48) TRPA1MAOBALOX15KDM4EMEN1
SCHEMBL1468384 0.77 TRPA1 (0.48) TRPA1MAOBALOX15KDM4EMEN1
SCHEMBL8990017 0.76 MAOB (0.48) TRPA1MAOBMEN1ALDH1A1MAPT
SCHEMBL17239119 0.76 HTR2A (0.40) TRPA1MAOBCYP2C19ALOX15KDM4E
SCHEMBL5807430 0.75 MAOB (0.42) TRPA1MAOBCYP2C19ALOX15EGFR
SCHEMBL3372078 0.73 TRPA1 (0.45) TRPA1MAOBALOX15CHATRELA
SCHEMBL3916137 0.72 MAOB (0.44) TRPA1MAOBALOX15MEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110333647-A A kind of positive type photosensitive organic compound 北京波米科技有限公司 2019-10-15 CN disclosed
CN-106795275-B Actinic-radiation curable composition 株式会社钟化 2019-03-05 CN disclosed
CN-106795275-A Actinic-radiation curable composition 株式会社钟化 2017-05-31 CN disclosed
CN-102292675-B Positive-type photosensitive resin composition TORAY INDUSTRIES 2012-08-22 CN disclosed
CN-101646959-B Lens NIPPON STEEL CHEMICAL CO 2012-06-27 CN disclosed
CN-101410437-B Curable resin, curable resin compositions and moldings thereof NIPPON STEEL CHEMICAL CO 2012-01-04 CN disclosed
CN-102292675-A Positive-type photosensitive resin composition 2011-12-21 CN disclosed
CN-101174053-B Display device NIPPON STEEL CHEMICAL CO 2011-04-20 CN disclosed
CN-101646959-A Lens NIPPON STEEL CHEMICAL CO JP 2010-02-10 CN disclosed
CN-101410437-A Curable resin, curable resin compositions and moldings thereof NIPPON STEEL CHEMICAL CO (JP) 2009-04-15 CN disclosed
CN-101174053-A Display device NIPPON STEEL CHEMICAL CO (JP) 2008-05-07 CN disclosed