Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.76 |
| ▸ | MAOA | P21397 | 2/20 | 0.76 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27723295 | 0.91 | KDM1A (0.63) | KDM1AMAOARAB9AMEN1KMT2A | |
| SCHEMBL27702830 | 0.91 | KDM1A (0.63) | KDM1AMAOARAB9AMEN1KMT2A | |
| SCHEMBL27702845 | 0.90 | KDM1A (0.65) | KDM1AMAOARAB9AMEN1KMT2A | |
| SCHEMBL27702843 | 0.88 | KDM1A (0.60) | KDM1AMAOARAB9AMEN1KMT2A | |
| SCHEMBL27856511 | 0.86 | ALDH1A1 (0.59) | KDM1AMAOARAB9AMEN1KMT2A | |
| SCHEMBL3555628 | 0.83 | HTR6 (0.65) | KDM1AMAOAMEN1KMT2APOLB | |
| SCHEMBL27702848 | 0.82 | RAB9A (0.57) | KDM1AMAOARAB9AMEN1KMT2A | |
| SCHEMBL8699498 | 0.81 | KDM1A (0.63) | KDM1AMAOARAB9AMEN1KMT2A | |
| SCHEMBL2825370 | 0.81 | KMT2A (0.79) | MEN1KMT2APOLBPFKFB3MAPT | |
| SCHEMBL17347402 | 0.80 | KDM1A (0.61) | KDM1AMAOAMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101189210-B | Sulfonamide derivatives useful as liver carnitine palmitoyl transferase (L-CPTl) inhibitors | HOFFMANN LA ROCHE | 2012-06-06 | — | — | CN | disclosed |
| CN-101189210-A | Sulfonamide derivatives useful as liver carnitine palmitoyl transferase (L-CPTl) inhibitors | HOFFMANN LA ROCHE (CH) | 2008-05-28 | — | — | CN | disclosed |