Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.63 |
| ▸ | MAOA | P21397 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8366113 | 0.82 | MEN1 (0.60) | KDM1AMAOAALDH1A1MAPTKMT2A | |
| SCHEMBL27723355 | 0.81 | KDM1A (0.76) | KDM1AMAOAALDH1A1MAPTKMT2A | |
| SCHEMBL17347402 | 0.80 | KDM1A (0.61) | KDM1AMAOAMAPTKMT2AMEN1 | |
| SCHEMBL7171823 | 0.76 | HTR6 (0.62) | KDM1AALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL8366885 | 0.76 | OPRM1 (0.51) | KDM1AMAOAKMT2AMEN1 | |
| SCHEMBL17347406 | 0.75 | LMNA (0.74) | KDM1AMAOAALDH1A1KMT2ARAB9A | |
| SCHEMBL5726019 | 0.74 | ALDH1A1 (0.63) | ALDH1A1MAPTKMT2ARAB9AMEN1 | |
| SCHEMBL8516967 | 0.74 | MEN1 (0.50) | KDM1AMAOAMAPTKMT2AMEN1 | |
| SCHEMBL29356619 | 0.74 | ALDH1A1 (0.77) | ALDH1A1MAPTKMT2ARAB9AMEN1 | |
| SCHEMBL6270935 | 0.74 | ALDH1A1 (0.77) | ALDH1A1MAPTKMT2ARAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741819-A | THROMBOSIS INHIBITORS; ANTIINFLAMMATORY AGENTS; NEURODEGENERATIVE DISORDERS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1998-04-21 | — | — | US | disclosed |