Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.48 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | TYRO3 | Q06418 | 7/20 | 0.43 |
| ▸ | MERTK | Q12866 | 7/20 | 0.43 |
| ▸ | FLT3 | P36888 | 5/20 | 0.43 |
| ▸ | AXL | P30530 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GAS6 | Q14393 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27708013 | 0.88 | NPC1 (0.45) | TLR7TYRO3MERTKFLT3AXL | |
| SCHEMBL27728529 | 0.87 | TYRO3 (0.45) | TLR7TLR8TYRO3MERTKFLT3 | |
| SCHEMBL27728421 | 0.77 | TLR7 (0.41) | TLR7TLR8HRH3TYRO3MERTK | |
| SCHEMBL27678180 | 0.76 | OXTR (0.44) | SMN1; SMN2KMT2ATSHRRAB9AMEN1 | |
| SCHEMBL27676108 | 0.76 | SOAT2 (0.52) | SMN1; SMN2TSHRRAB9ANPC1TP53 | |
| SCHEMBL9453146 | 0.72 | SOAT1 (0.58) | SMN1; SMN2TSHRRAB9ANPC1TP53 | |
| SCHEMBL27728431 | 0.71 | MAPK14 (0.45) | TLR7TLR8HRH3SMN1; SMN2KMT2A | |
| SCHEMBL28053394 | 0.71 | TP53 (0.44) | SMN1; SMN2KMT2ATSHRRAB9AMEN1 | |
| SCHEMBL28766878 | 0.71 | HTT (0.46) | SMN1; SMN2KMT2AMEN1LMNAMAPT | |
| SCHEMBL25137036 | 0.71 | HRH3 (0.62) | HRH3SMN1; SMN2KMT2ATSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101198607-A | Phenylacetamides suitable as protein kinase inhibitors | NOVARTIS AG (CH) | 2008-06-11 | — | — | CN | disclosed |