Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 2/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 7/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.40 |
| ▸ | SRC | P12931 | 2/20 | 0.40 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.40 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.40 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27728530 | 0.87 | NCF1 (0.45) | MAPK14TLR7SMN1; SMN2MEN1NPC1 | |
| SCHEMBL27721618 | 0.76 | RAB9A (0.50) | SMN1; SMN2MEN1NPC1TP53HPGD | |
| SCHEMBL25137036 | 0.76 | HRH3 (0.62) | HRH3SMN1; SMN2MEN1NPC1TP53 | |
| SCHEMBL5907253 | 0.75 | CYP2A13 (0.44) | MAPK14SMN1; SMN2NPC1TP53RAB9A | |
| SCHEMBL27678182 | 0.75 | KDM4E (0.52) | MAPK14SMN1; SMN2MEN1NPC1HPGD | |
| SCHEMBL27676109 | 0.75 | RAB9A (0.49) | MAPK14SMN1; SMN2MEN1NPC1TP53 | |
| SCHEMBL27705945 | 0.74 | SMN1; SMN2 (0.51) | TLR7HRH3SMN1; SMN2MEN1NPC1 | |
| SCHEMBL27728429 | 0.71 | TLR7 (0.48) | TLR7HRH3TLR8SMN1; SMN2MEN1 | |
| SCHEMBL27984253 | 0.70 | ELANE (0.38) | TLR8SMN1; SMN2MEN1NPC1HPGD | |
| SCHEMBL28053397 | 0.70 | ALDH1A1 (0.42) | SMN1; SMN2MEN1NPC1TP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101198607-A | Phenylacetamides suitable as protein kinase inhibitors | NOVARTIS AG (CH) | 2008-06-11 | — | — | CN | disclosed |