Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYRO3 | Q06418 | 4/20 | 0.45 |
| ▸ | MERTK | Q12866 | 4/20 | 0.45 |
| ▸ | AXL | P30530 | 2/20 | 0.45 |
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 2/20 | 0.40 |
| ▸ | GAS6 | Q14393 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27728429 | 0.87 | TLR7 (0.48) | TYRO3MERTKAXLNOS1TLR7 | |
| SCHEMBL27705944 | 0.78 | SMN1; SMN2 (0.53) | NCF1NOS1TLR7TLR8ALDH1A1 | |
| SCHEMBL28784326 | 0.76 | SOAT2 (0.41) | TLR7TLR8ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL27708013 | 0.76 | NPC1 (0.45) | TYRO3MERTKAXLTLR7ALDH1A1 | |
| SCHEMBL27676108 | 0.75 | SOAT2 (0.52) | ALDH1A1SMN1; SMN2HPGDKDM4ETP53 | |
| SCHEMBL27728530 | 0.74 | NCF1 (0.45) | NCF1NOS1TLR7ALDH1A1SMN1; SMN2 | |
| SCHEMBL5257716 | 0.71 | PDE4B (0.50) | ALDH1A1SMN1; SMN2HPGDHTTNPC1 | |
| SCHEMBL9453146 | 0.71 | SOAT1 (0.58) | ALDH1A1SMN1; SMN2HPGDKDM4ETP53 | |
| SCHEMBL28053394 | 0.70 | TP53 (0.44) | ALDH1A1SMN1; SMN2KDM4EHTTTP53 | |
| SCHEMBL11086699 | 0.70 | SOAT1 (0.60) | ALDH1A1SMN1; SMN2HPGDKDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101198607-A | Phenylacetamides suitable as protein kinase inhibitors | NOVARTIS AG (CH) | 2008-06-11 | — | — | CN | disclosed |