Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOX1 | Q06278 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALPG | P10696 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9802194 | 0.82 | AOX1 (0.47) | AOX1MEN1KMT2AHSP90AA1CFTR | |
| SCHEMBL808442 | 0.75 | MEN1 (0.39) | AOX1MEN1KMT2AHSP90AA1CFTR | |
| Bromide SCHEMBL28241411 | 0.73 | MEN1 (0.38) | AOX1MEN1KMT2AHSP90AA1CFTR | |
| SCHEMBL8190077 | 0.73 | GAA (0.41) | MEN1KMT2AHSP90AA1CFTRCA2 | |
| SCHEMBL7096547 | 0.73 | ALDH1A1 (0.36) | AOX1MEN1KMT2AHSP90AA1CFTR | |
| SCHEMBL27661786 | 0.73 | MEN1 (0.38) | AOX1MEN1KMT2AHSP90AA1CFTR | |
| SCHEMBL10665143 | 0.73 | HSP90AA1 (0.35) | AOX1MEN1KMT2AHSP90AA1CFTR | |
| SCHEMBL27728842 | 0.73 | HSP90AA1 (0.44) | MEN1KMT2AHSP90AA1CFTRCA2 | |
| SCHEMBL3115111 | 0.73 | USP2 (0.47) | MEN1KMT2AHSP90AA1CFTRCA2 | |
| SCHEMBL27646839 | 0.73 | HSP90AA1 (0.41) | AOX1MEN1KMT2AHSP90AA1CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101291933-B | Derivatives of 5-pyridazinyl-1-azabicyclo [3.2.1] octane, their preparation and their therapeutic use | SANOFI AVENTIS | 2012-03-14 | — | — | CN | disclosed |
| CN-101291933-A | Derivatives of 5-pyridazinyl-1-azabicyclo [3.2.1] octane, their preparation and their therapeutic use | SANOFI AVENTIS (FR) | 2008-10-22 | — | — | CN | disclosed |