Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 9/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.45 |
| ▸ | DRD2 | P14416 | 5/20 | 0.45 |
| ▸ | DRD3 | P35462 | 5/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD5 | P21918 | 1/20 | 0.43 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28922215 | 0.85 | OPRM1 (0.46) | OPRM1OPRD1OPRK1DRD2DRD3 | |
| SCHEMBL30763518 | 0.85 | OPRM1 (0.46) | OPRM1OPRD1OPRK1DRD2DRD3 | |
| SCHEMBL27553988 | 0.81 | TAAR1 (0.50) | — | |
| SCHEMBL22112040 | 0.78 | DRD2 (0.48) | OPRM1OPRD1OPRK1DRD2DRD3 | |
| SCHEMBL27729903 | 0.78 | ACHE (0.44) | — | |
| SCHEMBL19072758 | 0.78 | CYP1A2 (0.46) | OPRM1OPRK1 | |
| SCHEMBL14402697 | 0.77 | OPRM1 (0.47) | OPRM1OPRD1OPRK1DRD2DRD3 | |
| SCHEMBL1484276 | 0.77 | ESR1 (0.49) | — | |
| SCHEMBL8503783 | 0.76 | CSNK1E (0.51) | — | |
| SCHEMBL29411063 | 0.76 | SIGMAR1 (0.48) | OPRM1OPRD1OPRK1DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101228110-A | 3-(2-(dimethylamino)methyl(cyclohex-1-yl))phenol maleate and its crystalline for | GRUENENTHAL GMBH (DE) | 2008-07-23 | — | — | CN | claimed |
| CN-101228110-A | 3-(2-(dimethylamino)methyl(cyclohex-1-yl))phenol maleate and its crystalline for | GRUENENTHAL GMBH (DE) | 2008-07-23 | — | — | CN | disclosed |