Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | CASP6 | P55212 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | HCAR3 | P49019 | 7/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | EIF4E | P06730 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2772166 | 0.89 | TSHR (0.65) | TSHRMEN1KMT2APOLBCASP6 | |
| SCHEMBL2771400 | 0.81 | ESR1 (0.50) | TSHRMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL5696841 | 0.79 | TSHR (0.65) | TSHRMEN1KMT2APOLBCASP6 | |
| SCHEMBL272092 | 0.78 | TTR (0.56) | TSHRKMT2APOLBCES2CES1 | |
| SCHEMBL6555682 | 0.77 | POLB (0.59) | TSHRPOLBCASP6HCAR3LMNA | |
| SCHEMBL6555690 | 0.77 | POLB (0.59) | TSHRPOLBCASP6HCAR3LMNA | |
| Hydrochloric Acid SCHEMBL9784149 | 0.77 | CASP6 (0.62) | TSHRPOLBCASP6HCAR3LMNA | |
| SCHEMBL11195885 | 0.76 | CASP6 (0.75) | TSHRCASP6HCAR3LMNA | |
| SCHEMBL2773008 | 0.75 | VCAM1 (0.54) | MEN1KMT2APOLBCES2CES1 | |
| SCHEMBL99918 | 0.72 | CASP6 (0.64) | TSHRPOLBCASP6HCAR3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2193125-A2 | OXADIAZOLE DERIVATIVES | Merck Serono S.A. (CH) | 2010-06-09 | — | — | EP | disclosed |
| WO-2009043889-A2 | OXADIAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2009-04-09 | — | — | WO | disclosed |