Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 10/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.34 |
| ▸ | BRD1 | O95696 | 1/20 | 0.34 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | DAGLB | Q8NCG7 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27733849 | 0.88 | PPARG (0.36) | MAPTPKMPPARGPPARDPPARA | |
| SCHEMBL27733696 | 0.83 | PTGS1 (0.40) | MAPTPPARGPPARDPPARA | |
| SCHEMBL28770838 | 0.81 | ALDH1A1 (0.35) | MAPTPPARGPPARDPPARA | |
| SCHEMBL27733852 | 0.81 | PSEN1 (0.39) | PPARGPPARDPPARA | |
| SCHEMBL27713300 | 0.80 | NOTUM (0.45) | TRIM24MAPTRAB9A | |
| SCHEMBL27733711 | 0.80 | PPARG (0.41) | PPARGPPARDPPARA | |
| SCHEMBL27833766 | 0.78 | PHGDH (0.38) | PPARGPPARDPPARA | |
| SCHEMBL27867737 | 0.78 | SSTR5 (0.35) | DAGLASCN9APPARGPPARDPPARA | |
| SCHEMBL27733800 | 0.77 | FABP4 (0.40) | MAPTPKMPPARGPPARDPPARA | |
| SCHEMBL27733841 | 0.77 | F7 (0.36) | PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101248044-B | Indole compounds | FOURNIER LAB SA | 2012-05-30 | — | — | CN | disclosed |
| CN-101248044-A | Novel indole compounds | FOURNIER LAB SA (FR) | 2008-08-20 | — | — | CN | disclosed |